Suspected role of Chromium in disinhibition

I’m working on Chromium topic now. I can see that this mineral’s role is under-appreciated and under-researched. But what is known already hints that Chromium should have significant effect on behavior and some psychiatric disorders.

Chromium appears to serve a role of an amplifier of specific signalling cascades inside the cell.

The most known one is insulin signalling. Others are: Akt, PI3K, AMPK and a few others.

What is also interesting that the same signalling proteins are involved in the intracellular propagation of neurotransmissions.

I now started to suspect that chromium deficiency could be implicated in disinhibition and increased oxidative stress has a role in that. The pacifier enzyme GKS3b has a direct relationship with Akt protein, which uses Chromodulin to amplify its activity.

I will post a detailed note about Chromium soon (UPD: it’s here).

Example of “Chromium helps to lower disinhibition” can be suggested from this study.

Binge Eating Disorder is a manifestation of disinhibition. A stronger manifestation of disinhibition is seen in ADHD and in Tourette syndrome.