These are my own posts in the Facebook group "Tourette Syndrome: Research and Intervention" where I share relevant articles, own thoughts and discuss people's experience with medication and non-medication. Feel free to join the group if you would like to discuss related topics.

BTBD9 gene and TS
July 24, 2023
#BTBD9 #CRL3 #Tourette syndrome #Iron #Autophagy #MEIS1 #MAP2K5 #SKOR1 #RLS #IRP2
Traumatic Brain Injury impairs degradation of autophagosomes
July 21, 2023
#TBI #Autophagy
Pimozide promotes autophagy, used to lower tics
July 20, 2023
#Pimozide #Autophagy #UPR #Tourette syndrome #Schizophrenia #Psychosis
Reduced autophagy leads to reduction of GABA-A receptors
July 18, 2023
#Autophagy #GABA-A #p62 #SQSTM1
Role of Allopregnanolone in tics severity
July 5, 2023
#Allopregnanolone #Tics #Tourette syndrome #GABA #Interneurons
ARHGEF9 and startle disease
June 14, 2023
#ARHGEF9 #GSK3b #GABA receptors #Glycine receptors #Gephyrin
GSK3b inhibits CBS
March 24, 2023
Motor-like Tics are Mediated by Cannabinoid Receptor 2-dependent Mechanism
March 12, 2023
#ECS #CB2 #Tics #Endocannabinoids
Oxidative stress in Tourette's syndrome
March 12, 2023
Probiotics modulate Akt differently
March 2, 2023
#Akt #Probiotics #L. reuteri #B. Breve #S. cerevisiae #L. rhamnosus #L. acidophilus
Risperidone and Olanzapine induce ER stress
March 2, 2023
#Risperidone #Olanzapine #ER Stress #Obesity #Hypermetaoblism #Antipshycotics
Role of Vanadium in Akt signalling
February 27, 2023
#Vanadium #Akt #GSK3b #Chromium #Inositol #PI3K #SCD #Oxidative stress #PTP1B #PHLPP #FAS #PEPCK #PTEN
Myristic acid and Akt protein
February 25, 2023
#AKT #Myristic acid
NAD supresses Akt activation via SIRT7-FKBP51-PHLPP
February 25, 2023
#AKT #SIRT7 #NAD #PHLPP #FKBP51 #GSK3b
GSK3b regulates Gephyrin
February 20, 2023
#GSK3b #Gephyrin #GABA #Lithium
Ketamine is a GSK3b inhibitor
February 20, 2023
#GSK3b #Ketamine #OCD #Depression #AMPA
Myrrh essential oil is an nrf2 activator
February 18, 2023
#Essential oil #Myrrh #Nrf2 #HO-1 #Oxidative stress
GSK3b explained
February 17, 2023
#GSK3b #BDNF #Depression #Anxiety #UPR #REDD1 #mTOR #CHOP #IGF-1 #EGF #WNT #PKA #CaMK2 #PP2A #PP2B
Suspected role of Chromium in disinhibition
February 16, 2023
#Disinhibition #Binge Eating Disorder #Chromium
Dopamine signalling inhibits Akt, leading to activation of GSK3b
February 16, 2023
#Dopamine #GSK3b #Akt #Lithium
GSK3b the pacifier
February 10, 2023
#GSK3b #HIF1 #NRF2
Astrocyte metabolic coupling in Tourette syndrome pathogenesis
February 9, 2023
#Astrocytes #Tourette syndrome
Hypoxia increases ROS production and activates Nrf2
February 7, 2023
#Hypoxia #Nrf2 #Apnea #Oxidative stress
Hypoxia and GSK3b
February 6, 2023
#hypoxia #GSK3b #HIF-1 #OCD #Nrf2
Methylation potential and perception of pain
January 7, 2023
#Methylation potential #Pain #TRPA1
AMPK and fear extinction
November 16, 2022
#AMPK #Fear extinction
Redox homeostasis, DNA damage and OCD
November 14, 2022
#OCD #Oxidative Stress
High level of Endocannabinoids in CSF in TS
September 20, 2022
#Tourette Syndrome #ECS
Blocking sequential subcircuits in their hyperglutamatergic CSTC loop halts tics
September 8, 2022
#Tourette Syndrome #CSTC
DGLA is able to abolish tardive dyskinesia
July 27, 2022
#DGLA #GLA #Linoleic acid #Tardive dyskinesia #OCD #phospholipids #Tourette Syndrome #Heme #Iron
Cases of Tourette’s Syndrome and Aripiprazole
July 23, 2022
#Tourette Syndrome #Aripiprazole
Arachidonic acid synthesis requires heme
July 17, 2022
#Arachidonic acid #Iron #Heme #ECS
Maternal PUFA imbalance and anxiety in offsprings
July 17, 2022
#PUFA #phospholipids #anxiety
Canadian Guidelines for the Evidence Based treatment of Tourette Syndrome
July 16, 2022
#Tourette Syndrome #Guidelines
Altered phospholipid and creatine in OCD
July 12, 2022
#OCD #Phospholipids #Creatine
Cannabidiol induces antioxidant pathways
June 24, 2022
#CBD #ECS #NRF2 #Oxidative stress #BACH1
Tricyclic Antidepressant and ECS
June 23, 2022
#ECS #antidepressants
Paracetamol and ECS
June 22, 2022
#Paracetamol #Acetaminophen #ECS #FAAH #Tics #Thoughts
Quality of Life and a Surveillant Endocannabinoid System
June 22, 2022
#ECS #anxiety #depression
Medicinal cannabis markedly reduced OCD
June 22, 2022
#OCD #Cannabis #ECS #Case report
Neuropulse announcement
June 21, 2022
#neuropulse #Wearable
A clinical trial launched for a wearable device for TS
June 4, 2022
#Clinical trial #Wearable
Iron deficiency in mothers is associated with tics disorder in children
May 31, 2022
#Iron #Tics #Tourette syndrome
Vitamin D and pediatric OCD
May 30, 2022
#Case Report #Vitamin D #OCD
Oral Iron Administration
May 25, 2022
#Iron #Ferritin #Anxiety #Depression #Concentration #Insomnia
Trace elements and tics disorder
May 25, 2022
#Zinc #Copper #Iron #Tics #Tourette syndrome
PANS and low ferritin
May 25, 2022
#Ferritin #Iron #PANS
Serum ferritin level and tic severity
May 25, 2022
#Tourette Syndrome #Ferritin #Iron #Tics
OCD and CBS
May 25, 2022
#OCD #CBS
Impaired PPI and Omega-3 deficiency
May 21, 2022
#Prepulse Inhibition #DHA #OCD #PPI