Research Notes by Sergey
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January 28, 2024

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References

Guanfacine stabilizes lysosomes in high oxidative stress

Guanfacine - medication used to lower tics - appears to stabilize lysosomes and prevent their rupturing in high oxidative stress environment.

This is interesting and in line with my current hypothesis that lysosomal dysfunction may be a factor in tics development.

References

1
Imidazoline drugs stabilize lysosomes and inhibit oxidative cytotoxicity in astrocytes
2002
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