Clerodendrum inerme stopped tics
We report on a 13-year-old girl, with chronic motor tic disorder refractory to multiple anti-tic therapies, who showed dramatic improvement and remission after taking the crude leaf extract of Clerodendrum inerme (L) Gaertn. No side effects were observed during a follow-up of more than 2 years. To the best of our knowledge, this is the first report on the anti-tic effect of Clerodendrum inerme. (R1)
I found this study when I was searching for “Betulinic acid” - a plant metabolite that activate proteasome.
I’m still researching whether proteasomal dysregulation is implicated in tics and OCD because I have several clues that point to that direction.
Pharmacological studies demonstrated that the extract of C. inerme_ exhibits a wide range of biological activities, such as antioxidant, antimicrobial, anticancer, antiinflammatory, insecticidal, antifeedant, neuroprotective, anti-motor tic, and so on. (R2)
About Clerodendrum inerme (L.) Gaertn
Other names of this plant:
- Glory Bower
- Garden Quinine
- Ku Lang Shu (chinese name)
- Chhoti Ari, Sankuppi, Sangan Kuppi, Vilayati Mehendi, Batraj (Hindi name) (Ref)