PANS and low ferritin

Our study suggests hypoferritinemia and iron deficiency are more common in patients with pediatric acute-onset neuropsychiatric syndrome (PANS) than in the sex- and age-matched US population.

Hypoferritinemia was commonly observed during a disease flare but not associated with dietary or demographic factors.

In patients with PANS and iron deficiency, clinicians should consider possibility of inflammation as the cause especially if iron deficiency cannot be explained by diet and blood loss.

Reference

1. Hypoferritinemia and iron deficiency in youth with pediatric acute-onset neuropsychiatric syndrome, 2021 / Pubmed