Research Notes by Sergey
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April 1, 2023
  • #Arsenic
  • #Methylation
  • #GSH

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References

Arsenic detox by AS3MT

Arsenic is detoxified in human bodies by glutathionylation and methylation, which is done by AS3MT (Arsenite methyltransferase).

Arsenic binds to three molecules of GSH first, and then arsenic triglutathione is methylated, and a molecule of water is used. This reaction releases GSH, SAH and trimethylarsenite.

References

1
Uniprot: AS3MT
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