Chromium has a positive effect on oxidative stress

It seems Chromium has a positive effect on oxidative stress. Based on upregulated transcriptions it likely does so by activating Nrf2 pathway:

An upregulation of the transcripts of glutathione synthetase, heme oxygenase-2, and peroxiredoxin was observed in cells treated with chromium.

In addition, chromium inhibited hydrogen peroxide-mediated oxidation of thiols and lipid peroxidation.

Chromium supplementation in obese mice significantly attenuated the obesity-associated elevated ratio of oxidized glutathione to reduced glutathione and the formation of protein carbonyl.