Batten Disease
Batten disease Lysosome
DRAM1 is a novel susceptibility locus identified in TS
Tourette Syndrome Autophagy Lysosome DRAM1
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Chloroquine Autophagy Lysosome
DHA inhibits proteolysis
Tics DHA Lysosome Proteasome Ubiquitin Autophagy
Copper is a cofactor of SUMF1
Copper SUMF1 Lysosome Lysosomal Storage Disorder Multiple Sulfatase Deficiency Sulfatases
Role of excessive ubiquitination in BH4 deficiency
BH4 Tetrahydrobiopterin GTPCH1 Ubiquitination p62 Hypertension Diabetes Mellitus 2 Autophagy Lysosome
Beta-Mannosidase Deficiency and TS
Tourette Syndrome Beta-mannosidase deficiency MANBA Lysosome Mental retardation Hearing loos Behavior Infections Mannose N-acetylglucosamine NAG
Cystine
Cystine CTNS Lysosome Melanosome melanin
Vitamin B12 metabolism
Glutathione Cobalamin SAMe ZNF143 HCFC1 MMACHC Lysosome mTORC1