RSAD1 is a heme chaperone catalyzing the insertion of heme into hemoproteins
heme iron SAMe RSAD1
SAMe deficiency impairs assembly of OXPHOS
SAMe Mitochondria Complex I Methylation Iron-Sulfur clusters
Excess S-Adenosylmethionine inhibits methylation via catabolism to adenine
SAMe Circadian Methylation
Vitamin B12 metabolism
Glutathione Cobalamin SAMe ZNF143 HCFC1 MMACHC Lysosome mTORC1
SAMe stabilizes CBS enzyme
CBS SAMe Oxidative stress