Cannabidiol induces antioxidant pathways

Ah, turns out CBD also induces Nrf2 and the downstream genes that are related to antioxidant defense system.

No wonder it helps to reduce anxiety (in case if that is caused by high oxidative stress) and tics (the same reasons).

And this also means, that in case of insufficient selenium or in presence of Mercury, CBD, like any other Nrf2 activator, have a good chance to produce negative symptoms because the enzyme TXNRD, which is supposed to be helping, will amplify oxidative stress instead of reducing it - because this is what it does when there not enough selenium or even mild mercury poisoning.