Below you will find pages that utilize the taxonomy term “Nrf2”

Metabolic Dangers of Nrf2 activation
November 17, 2024
#Nrf2 #KEAP1 #NAD #ALDH3A1 #Reductive Stress
L-selenocystine is toxic for Nrf2 addicted cells
November 10, 2024
#Nrf2 #Selenocystine #Autophagy #p62 #KEAP1 #Oxidative Stress #AKT #mTOR #ULK1 #Beclin1 #
Activation of WNT3A prevents deactivation of Nrf2 by GSK3b
August 25, 2024
#WNT3A #Nrf2 #GKS3b #Axin1
MAPK, p62, autophagy and inflammation
June 18, 2024
#MAPK #SQSTM1 #p62 #Autophagy #GABA-A Receptor #ULK1 #Inflammation #NRF2
Higher Nrf2 activation may be needed for activating metabolic genes vs. cytoprotective genes
June 3, 2024
#Nrf2 #PI3K #Akt #PTEN #KEAP1
Nrf2 activation leads to imbalance of carbon metabolism
May 3, 2024
#NRF2 #Glutamine #Glutamate #GSH #KEAP1 #xCT
O‐GlcNAcylation
April 29, 2024
#O‐GlcNAcylation #Glycosylation #OGT #OGA #KEAP1 #NRF2 #NRF1
Oxidative stress lowers testosterone production
April 27, 2024
#SIRT1 #NRF2 #Testosterone #Progesterone #NAM #Niacinamide #Oxidative stress #Hypogonadism #Luteinizing hormone
Amoxicillin decreased KEAP1, CPT1, CHOP expression and PPARa transactivation
April 20, 2024
#Amoxicillin #NRF2 #KEAP1 #CPT1 #CHOP #PPARa #Carnitine #Tics
Progesterone inhibits GSK3b
March 25, 2024
#Progesterone #GSK3b #Nrf2 #Akt #Chromium #Vanadium #Menstrual Cycle
Genetic overactivation of Nrf2: consequences and treatment
February 11, 2024
#Nrf2 #NFE2L2 #Luteolin #Ascorbic acid #Immunodeficiency #Hyperkeratosis #Hypohomocysteinaemia #G6PD
Nrf2 target genes
January 27, 2024
#Nrf2
Role of MAFF in dampening Nrf2 signal
October 22, 2023
#Nrf2 #MAFF #Hypoxia #HIF1 #IL1b #TNFa #Cytokines
Inhibited autophagy blocks xCT transport to the membrane
July 18, 2023
#Autophagy #Nrf2 #xCT #SLC7A11 #Cystine
Boron
July 13, 2023
#Boron #Nrf2
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury
May 23, 2023
#Nrf2 #Cadmium #KEAP1 #autophagy
Elevated ethylmalonic acid can be a result of Nrf2 activation
May 3, 2023
#Nrf2 #Cystine #Persulfides #xCT #SLC7A11 #SQOR
Excessive cysteine, H2S and PPI
March 31, 2023
#PPI #H2S #Cysteine #ETC #RET #Nrf2
Zinc
March 20, 2023
#Zinc #Nrf2 #Akt #GSK3b
Akt is the first responder. Essential role of Vanadium
March 2, 2023
#Akt #Nrf2 #Vanadium #Chromium
Signalling cascades
February 23, 2023
#Nrf2 #PI3K #GSK3b #Akt #WNT #Beta-catenin #AMPK
Myrrh essential oil is an nrf2 activator
February 18, 2023
#Essential oil #Myrrh #Nrf2 #HO-1 #Oxidative stress
GSK3b the pacifier
February 10, 2023
#GSK3b #HIF1 #NRF2
Hypoxia increases ROS production and activates Nrf2
February 7, 2023
#Hypoxia #Nrf2 #Apnea #Oxidative stress
Hypoxia and GSK3b
February 6, 2023
#hypoxia #GSK3b #HIF-1 #OCD #Nrf2
PGC-1a
January 15, 2023
#PGC1a #Nrf1 #Nrf2 #Fat oxidation #Fasting #Resveratrol #Methionine cycle #Mitochondria #Schizophrenia #CQ10 #RXR #Retinoic acid
AMPK
November 19, 2022
#AMPK #Iron deficiency #Nrf2 #Chromium
Nrf2
June 27, 2022
#Nrf2 #Oxidative stress
Nrf2 activation depends on NAD status
June 24, 2022
#Nrf2 #NAD #BACH1 #SIRT6
Cannabidiol induces antioxidant pathways
June 24, 2022
#CBD #ECS #NRF2 #Oxidative stress #BACH1
Uranium inhibits Nrf2 activity
May 31, 2022
#Uranium #Nrf2 #CSE #CBS #H2S
Nrf2's ability to activate is dependent on methylation
December 5, 2021
#Nrf2 #Methylation potential
Binding of Nrf2 to DNA is increased by methylation
November 30, 2021
#Methylation #PRMT1 #Nrf2
Overactivation of Nrf2 induced tics
November 22, 2021
#Nrf2 #Tics
Overactivation of Heme Oxigenase 1 early in life leads to symptoms similar to schizophrenia or Parkinson's disease
November 21, 2021
#Schizophrenia #HMOX1 #HO1 #Nrf2 #Oxidative stress #PPI #Hyperkinesia #olfaction
Alternative explanation now Nrf2 activation works
November 17, 2021
#Nrf2 #KEAP1
Inactivation of TrxR1 leads to Nrf2 activation
November 17, 2021
#TXNRD1 #Selenium #Nrf2 #KEAP1
Mercury inhibits Nrf2 activity
November 14, 2021
#Mercury #Nrf2 #Selenium
Chronic oxidative stress impairs Nrf2 activation
September 4, 2021
#Nrf2 #Oxidative stress
Retinoic acid inhibits Nrf2
August 21, 2021
#Retinoic acid #Nrf2
Chromium
June 5, 2021
#Chromium #NRF2 #Oxidative Stress #AMPK #Akt #GLUT4 #eNOS #ACC #TNF-alpha #IL-6 #CRP #ER stress
Addressing Glutathione Depletion
May 16, 2021
#Glutathione #Nrf2 #Sulforaphane #MSM #Resveratrol #Ascorbic acid