Energy deprivation inhibits Akt
Akt AMPK Energy PI3K IRS-1
Autophagy
Autophagy HIF1 AMPK ATG ULK1 mTORC1 Glycogen
Signalling cascades
Nrf2 PI3K GSK3b Akt WNT Beta-catenin AMPK
Creatine activates AMPK and induces PGC1a
Creatine PGC1a AMPK
AMPK
AMPK Iron deficiency Nrf2 Chromium
AMPK and fear extinction
AMPK Fear extinction
Chromium
Chromium NRF2 Oxidative Stress AMPK Akt GLUT4 eNOS ACC TNF-alpha IL-6 CRP ER stress