Deregulated Nrf2-Keap1-BACH1 axis in autism spectrum disorder
NRF2 BACH1 Autism ASD Tics p62 Heme Iron
Heme
Heme ALAS
Ferrochelatase (overview)
FECH Heme Iron Ferrochelatase
Inhibition of FECH and Photosensitivity
Photosensitivity FECH Ferrochelatase Heme
RSAD1 is a heme chaperone catalyzing the insertion of heme into hemoproteins
heme iron SAMe RSAD1
Serine
Serine Heme Glutamate NAD SHMT
Nrf2 might be inhibiting heme synthesis
Heme Iron SFN ALAD
DGLA is able to abolish tardive dyskinesia
DGLA GLA Linoleic acid Tardive dyskinesia OCD phospholipids Tourette Syndrome Heme Iron
Arachidonic acid synthesis requires heme
Arachidonic acid Iron Heme ECS
Heme biosynthesis depends on acquisition of iron-sulfur cofactor
Heme Porphyrins Iron