Research Notes by Sergey
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Below you will find pages that utilize the taxonomy term “KEAP1”
Metabolic Dangers of Nrf2 activation
November 17, 2024
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Nrf2
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KEAP1
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NAD
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ALDH3A1
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Reductive Stress
L-selenocystine is toxic for Nrf2 addicted cells
November 10, 2024
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Nrf2
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Selenocystine
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Autophagy
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p62
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KEAP1
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Oxidative Stress
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AKT
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mTOR
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ULK1
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Beclin1
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Higher Nrf2 activation may be needed for activating metabolic genes vs. cytoprotective genes
June 3, 2024
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Nrf2
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PI3K
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Akt
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PTEN
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KEAP1
Nrf2 activation leads to imbalance of carbon metabolism
May 3, 2024
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NRF2
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Glutamine
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Glutamate
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GSH
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KEAP1
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xCT
O‐GlcNAcylation
April 29, 2024
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O‐GlcNAcylation
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Glycosylation
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OGT
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OGA
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KEAP1
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NRF2
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NRF1
Amoxicillin decreased KEAP1, CPT1, CHOP expression and PPARa transactivation
April 20, 2024
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Amoxicillin
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NRF2
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KEAP1
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CPT1
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CHOP
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PPARa
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Carnitine
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Tics
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury
May 23, 2023
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Nrf2
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Cadmium
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KEAP1
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autophagy
Alternative explanation now Nrf2 activation works
November 17, 2021
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Nrf2
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KEAP1
Inactivation of TrxR1 leads to Nrf2 activation
November 17, 2021
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TXNRD1
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Selenium
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Nrf2
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KEAP1