Research Notes by Sergey
🔍
Notes
Posts
Hypotheses
About Author
Below you will find pages that utilize the taxonomy term “Nrf2”
Deregulated Nrf2-Keap1-BACH1 axis in autism spectrum disorder
Aug 26, 2025
NRF2
BACH1
Autism
ASD
Tics
p62
Heme
Iron
Apple's content activate Nrf2
Jan 11, 2025
Apple
Nrf2
Metabolic Dangers of Nrf2 activation
Nov 17, 2024
Nrf2
KEAP1
NAD
ALDH3A1
Reductive Stress
L-selenocystine is toxic for Nrf2 addicted cells
Nov 10, 2024
Nrf2
Selenocystine
Autophagy
p62
KEAP1
Oxidative Stress
AKT
mTOR
ULK1
Beclin1
Activation of WNT3A prevents deactivation of Nrf2 by GSK3b
Aug 25, 2024
WNT3A
Nrf2
GKS3b
Axin1
MAPK, p62, autophagy and inflammation
Jun 18, 2024
MAPK
SQSTM1
p62
Autophagy
GABA-A Receptor
ULK1
Inflammation
NRF2
Higher Nrf2 activation may be needed for activating metabolic genes vs. cytoprotective genes
Jun 3, 2024
Nrf2
PI3K
Akt
PTEN
KEAP1
Nrf2 activation leads to imbalance of carbon metabolism
May 3, 2024
NRF2
Glutamine
Glutamate
GSH
KEAP1
xCT
O‐GlcNAcylation
Apr 29, 2024
O‐GlcNAcylation
Glycosylation
OGT
OGA
KEAP1
NRF2
NRF1
Oxidative stress lowers testosterone production
Apr 27, 2024
SIRT1
NRF2
Testosterone
Progesterone
NAM
Niacinamide
Oxidative stress
Hypogonadism
Luteinizing hormone
Amoxicillin decreased KEAP1, CPT1, CHOP expression and PPARa transactivation
Apr 20, 2024
Amoxicillin
NRF2
KEAP1
CPT1
CHOP
PPARa
Carnitine
Tics
Progesterone inhibits GSK3b
Mar 25, 2024
Progesterone
GSK3b
Nrf2
Akt
Chromium
Vanadium
Menstrual Cycle
Genetic overactivation of Nrf2: consequences and treatment
Feb 11, 2024
Nrf2
NFE2L2
Luteolin
Ascorbic acid
Immunodeficiency
Hyperkeratosis
Hypohomocysteinaemia
G6PD
Nrf2 target genes
Jan 27, 2024
Nrf2
Role of MAFF in dampening Nrf2 signal
Oct 22, 2023
Nrf2
MAFF
Hypoxia
HIF1
IL1b
TNFa
Cytokines
Inhibited autophagy blocks xCT transport to the membrane
Jul 18, 2023
Autophagy
Nrf2
xCT
SLC7A11
Cystine
Boron
Jul 13, 2023
Boron
Nrf2
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury
May 23, 2023
Nrf2
Cadmium
KEAP1
autophagy
Elevated ethylmalonic acid can be a result of Nrf2 activation
May 3, 2023
Nrf2
Cystine
Persulfides
xCT
SLC7A11
SQOR
Excessive cysteine, H2S and PPI
Mar 31, 2023
PPI
H2S
Cysteine
ETC
RET
Nrf2
Zinc
Mar 20, 2023
Zinc
Nrf2
Akt
GSK3b
Akt is the first responder. Essential role of Vanadium
Mar 2, 2023
Akt
Nrf2
Vanadium
Chromium
Signalling cascades
Feb 23, 2023
Nrf2
PI3K
GSK3b
Akt
WNT
Beta-catenin
AMPK
Myrrh essential oil is an nrf2 activator
Feb 18, 2023
Essential oil
Myrrh
Nrf2
HO-1
Oxidative stress
GSK3b the pacifier
Feb 10, 2023
GSK3b
HIF1
NRF2
Hypoxia increases ROS production and activates Nrf2
Feb 7, 2023
Hypoxia
Nrf2
Apnea
Oxidative stress
Hypoxia and GSK3b
Feb 6, 2023
hypoxia
GSK3b
HIF-1
OCD
Nrf2
PGC-1a
Jan 15, 2023
PGC1a
Nrf1
Nrf2
Fat oxidation
Fasting
Resveratrol
Methionine cycle
Mitochondria
Schizophrenia
CQ10
RXR
Retinoic acid
AMPK
Nov 19, 2022
AMPK
Iron deficiency
Nrf2
Chromium
Nrf2
Jun 27, 2022
Nrf2
Oxidative stress
Nrf2 activation depends on NAD status
Jun 24, 2022
Nrf2
NAD
BACH1
SIRT6
Cannabidiol induces antioxidant pathways
Jun 24, 2022
CBD
ECS
NRF2
Oxidative stress
BACH1
Uranium inhibits Nrf2 activity
May 31, 2022
Uranium
Nrf2
CSE
CBS
H2S
Nrf2's ability to activate is dependent on methylation
Dec 5, 2021
Nrf2
Methylation potential
Binding of Nrf2 to DNA is increased by methylation
Nov 30, 2021
Methylation
PRMT1
Nrf2
Overactivation of Nrf2 induced tics
Nov 22, 2021
Nrf2
Tics
Overactivation of Heme Oxigenase 1 early in life leads to symptoms similar to schizophrenia or Parkinson's disease
Nov 21, 2021
Schizophrenia
HMOX1
HO1
Nrf2
Oxidative stress
PPI
Hyperkinesia
olfaction
Alternative explanation how Nrf2 activation works
Nov 17, 2021
Nrf2
KEAP1
Inactivation of TrxR1 leads to Nrf2 activation
Nov 17, 2021
TXNRD1
Selenium
Nrf2
KEAP1
Mercury inhibits Nrf2 activity
Nov 14, 2021
Mercury
Nrf2
Selenium
Chronic oxidative stress impairs Nrf2 activation
Sep 4, 2021
Nrf2
Oxidative stress
Retinoic acid inhibits Nrf2
Aug 21, 2021
Retinoic acid
Nrf2
Chromium
Jun 5, 2021
Chromium
NRF2
Oxidative Stress
AMPK
Akt
GLUT4
eNOS
ACC
TNF-alpha
IL-6
CRP
ER stress
Addressing Glutathione Depletion
May 16, 2021
Glutathione
Nrf2
Sulforaphane
MSM
Resveratrol
Ascorbic acid